Study: Adverse events following COVID-19 virus vaccination in Japanese young population: The first cross-sectional study conducted by a questionnaire survey after the first-time-injection. The liver received the highest dose (0.360 mSv/MBq), followed by the gallbladder wall (0.155 mSv/MBq). Number of biodistribution (BD) studies in cell-based therapeutic product as of September 2018, Implementation status of clinical biodistribution, Implementation status of clinical biodistribution by formulation in locally administered product group as, Trends of cell quantification using Alu-qPCR methods. In fragile patients receiving the blood, the damage could be lethal. The biodistribution study obtained by Bridle showed that the lipid nanoparticles in the vaccine did not remain . Pfizer's now infamous biodistribution study that was part of a pharmacokinetic package done for the Japanese government found that the LNP's go everywhere and anywhere, with special affinity for the liver, spleen, and ovaries. The current study investigated SARS-CoV-2 viral load, biodistribution and anti-SARS-CoV-2 antibody formation in patients suffering from severe corona virus disease 2019 (COVID-19) induced acute respiratory distress syndrome (ARDS). https://t.co/bvncGZWV4v pic.twitter.com/aNxH6bkAS5. What is the clinical outcome? *, o LNP=LipoNanoParticle which carries the mRNA, o LC-MS/MS is liquid chromatography with tandem mass spectrometry. . In a separate study, mice received IV injection of an imaging dose of [ 52 Mn]MnCl 2, followed by in vivo imaging by positron emission tomography (PET) and ex vivo biodistribution. If your mitochondria are already dysfunctional, the SARS-CoV-2 virus can more easily knock out more mitochondria, resulting in severe illness and death. Specific alterations make it far more toxic than that found on the virus itself. Before Increased oxidative stress may lead to endothelial dysfunction and aggravate systemic and local inflammation, thus contributing to acute lung injury, cytokine storm, and thrombosis seen in severe COVID-19 illness , A recent algorithm showed that majority of SARS-CoV-2 genomic and structural RNAs are targeted for mitochondrial matrix. Future Perspectives for Factor V Deficiency Using Recombinant and Advanced Therapies. Technically, it is not following the mRNA vaccine itself but following where the LNP container-luciferine goes as a surrogate to understanding where the mRNA may go. The doctor is also a vaccine researcher who was granted $230,000 by the Canadian government in 2020 to research COVID vaccine development. Assessments of shedding can be utilized . A biodistribution study of the Pfizer Covid-19 injection suggests a suspension of the use of mRNA 'Vaccines' is urgently required and blood donor organisations need to take a long hard look at their policies surrounding the acceptance of donations of blood from people who have received an mRNA based Covid-19 injection. It was a pre-clinical biodistribution study. The biodistribution study of [89 Zr]Zr-DFO-TST001 demonstrated favorable pharmacokinetics with a relatively long half-life in vivo (Fig. The current study investigated SARS-CoV-2 viral load, biodistribution and anti-SARS-CoV-2 antibody formation in patients suffering from severe corona virus disease 2019 (COVID-19) induced acute respiratory distress syndrome (ARDS). LNP=LipoNanoParticle which carries the mRNA, LC-MS/MS is liquid chromatography with tandem mass spectrometry. Because the synthetic mRNA in the vaccine has been programmed to instruct your cells to produce an unnatural, genetically engineered spike protein. Very often, the damage is caused by the immune system going on the attack, damaging blood vessel walls, and removing several of the anti-clotting mechanisms. The end result can be lethal, and this chain of events is exactly what these COVID-19 vaccines are setting into motion. The #CoronavirusFacts database records fact-checks published since the beginning of the COVID-19 outbreak. At first glance, this information seems relatively straightforward. 2021 Sep 8;22(18):9705. doi: 10.3390/ijms22189705. This not only leads to impaired MAVS [mitochondrial antiviral signaling] response but also aggravates inflammation and cell death.. Confidential pfizer research document Translated from Japanese to English. 2012 Mar;64(3):375-83. doi: 10.1002/acr.21558. Rightly, Bridle is extremely troubled about the current drive to vaccinate children against COVID-19, recently stating insufficient evidence exists to claim the benefits outweigh the risk of vaccinating the younger population. Image . 12 . Using Luciferine to follow biodistribution of a product is common practice. In this work, we have confirmed results in the literature and . A total of 4,653,566 medical personnel and 5,734,023 people aged 65 and over had received at Information on the biodistribution (BD) of cell therapy products (CTPs) is essential for prediction and assessment of their efficacy and toxicity profiles in non-clinical and clinical studies. The .gov means its official. Bittorf P, Bergmann T, Merlin S, Olgasi C, Pullig O, Sanzenbacher R, Zierau M, Walles H, Follenzi A, Braspenning J. Mol Ther Methods Clin Dev. The mouse study used three female BALB-c mice per group and luciferase protein expression was determined by in vivo bioluminescence readouts using an In Vivo Imaging System (IVIS) following injection of the luciferase substrate luciferine. And of particular concern for me is it accumulates in the ovaries, in quite high concentrations.. The vaccine-induced spike protein does not do this. Clipboard, Search History, and several other advanced features are temporarily unavailable. People will continue to gather evidence supporting the vaccine, and people will continue to gather evidence against the vaccine. (LogOut/ 2021 The Japanese Society for Regenerative Medicine. This is about as diabolical as it gets. An official website of the United States government. Dr Joseph Mercola Story at-a-glance Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., has gained access to Pfizer's biodistribution study from the Japanese regulatory agency. Support responsible news and fact-based information today! Biodistribution assays are performed to determine the in vivo distribution or localization of a drug product in selected species to support early biotherapeutic drug development. Click to access 672212000_30300AMX00231_I100_1.pdf, Pingback: Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated The Courtenay Turner Podcast. PLoS One. We thought the spike protein was a great target antigen; we never knew the spike protein itself was a toxin and was a pathogenic protein. Manipulation of mitochondria by virus may lead to mitochondrial dysfunction and increased oxidative stress ultimately leading to loss of mitochondrial integrity and cell death , Mitochondrial fission enables removal of the damaged portion of a mitochondrion to be cleared by mitophagy (a special form of autophagy). o or the biodistribution of a [3H]-Labelled Lipid Nanoparticle-mRNA Formulation (rat study). and when exactly? Change), You are commenting using your Facebook account. In summary, normally, the spike protein on a virus will collapse on itself and fall into the cell once it attaches to the ACE2 receptor. This is in contrast to current thinking the mRNA vaccine is quickly broken down at its site of injection in the arm implying no distribution to other organs. Recently, there has been speculation regarding potential safety signals associated with COVID-19 mRNA vaccines. He explained that, through cutting edge, peer-reviewed science, weve learned more about the many problems associated with spike proteins and COVID-19 vaccines: The SARS-CoV-2 has aspike protein on its surface. Shedding is the dissemination of the viral vectors (e.g. While all of this is highly problematic, there is help. Explanation: We deem this post as disinformation when it is claimed that the spike protein attacks the ovaries, the neurological system, and other organs. The biodistribution of hybrid nanostructures is a major subject of current nanomedical research. I wanted links for my wife who is Japanese and could not understand my resistance to them. Total recovery (% of injected dose) of radiolabeled LNP+modRNA outside the injection site was greatest in the liver (up to 21.5%) and was much less in spleen (1.1%), adrenal glands (0.1%) and ovaries (0.1%). When that happens, it can cause platelets to clump together, resulting in blood clots, and/or cause abnormal bleeding, Pfizer documents submitted to the European Medicines Agency also show the company failed to follow industry-standard quality management practices during preclinical toxicology studies and that key studies did not meet good laboratory practice standards. Over 48 hours, distribution from the injection site to most tissues occurred, with the majority of tissues exhibiting low levels of radioactivity. Not so. Bridle cites research showing that laboratory animals injected with purified spike protein from SARS-CoV-2 straight into their bloodstream developed cardiovascular problems and brain damage. Here in fact he spells out that the Japanese Pfizer biodistribution studies have found a high concentration of the Lipid Nanoparticles in the ovaries--a known result to Pfizer and the FDA . If the damage is serious enough, uncontrolled cell death can occur, which in turn leaks mitochondrial DNA (mtDNA) into your bloodstream.13, Aside from being detected in cases involving acute tissue injury, heart attack and sepsis, freely circulating mtDNA has also been shown to contribute to a number of chronic diseases, including systemic inflammatory response syndrome or SIRS, heart disease, liver failure, HIV infection, rheumatoid arthritis and certain cancers.14 As explained in COVID-19: A Mitochondrial Perspective:15. As a public-health body safeguarding medicines in the European Union (EU), EMA only recommends approval of a vaccine for COVID-19 after a thorough evaluation demonstrating the same high . Moreover, ascientific paper just accepted for publicationin the Oxford University Press for the Infectious Diseases Society of America supports this frightening hypothesis. The study is titled, "Placebo-controlled randomized double-blind (evaluators, patients) multi-facility joint parallel-group comparison . 2 Research, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, Japan. mRNA-1273 . As such, it seemed really risky to instruct the bodys cells to produce the very thing that causes severe problems. The second source Bridle cited during his interview is a "biodistribution study" obtained from the Japanese Pharmaceuticals and Medical Devices Agency. Princess Bajrakitiyabha of Thailand collapses, Vaxxed and unvaxxed coming down with same ailments, Sasha Latypova reveals COVID law and contracts, Todd Callender explains the legal framework for pandemics, Sasha Latypova gives a speech in Stockholm, Centers for Disease Control and Prevention, Fact Sheet for Healthcare Providers Administering Vaccine, https://www.fda.gov/media/144413/download, https://uncoverdc.com/wp-content/uploads/2021/05/Bridle.pdf.pagespeed.ce.aKOeaMY9Wh.pdf, https://omny.fm/shows/on-point-with-alex-pierson/new-peer-reviewed-study-on-covid-19-vaccines-sugge, https://www.lifesitenews.com/news/vaccine-researcher-admits-big-mistake-says-spike-protein-is-dangerous-toxin/, https://trialsitenews.com/did-pfizer-fail-to-perform-industry-standard-animal-testing-prior-to-initiation-of-mrna-clinical-trials/, https://www.youtube.com/watch?v=Du2wm5nhTXY, https://www.bitchute.com/video/UfFOTCxRORsp/, https://www.bitchute.com/video/T71ZVNAXi0jW/, https://rumble.com/v15oqc7-dr.-richard-urso-the-explosion-of-cancer-and-latent-disease-from-the-vaccin.html, First case of autopsy in a patient vaccinated against COVID-19, Report: mRNA vaccines is converted to DNA in the liver, Vaccine-Induced Covid-19 Mimicry Syndrome, Brian Gerrish explains the psychological manipulation of the public . 2015;99(23):99079922. Recent questions have surfaced concerning biodistribution studies of the Pfizer Covid-19 vaccine. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines, The assumption that vaccine developers have been working with is that the mRNA in the vaccines would primarily remain in and around the vaccination site. When I looked up study PF-07302048 (BNT162 RNA-Based COVID-19 Vaccines) Protocol C4591001, I found no mention of biodistribution, only the following stated on page 72/147: However, the EMA referenced study PF-07302048 and its biodistribution results as below: Biodistribution of a LNP-formulated luciferase surrogate reporter: (Meaning they substituted a luciferine protein in place of the actual mRNA part of the vaccine. Fact Sheet for Healthcare Providers Administering Vaccine [Pfizer-BioNTech]. No, the Japanese biodistribution study shows nothing of the sort. National Library of Medicine No safety pharmacology studies were conducted with BNT162b2. Copyright 2023 Pandemic Timeline. Whats more, TrialSite News reports6 that Pfizer documents submitted to the European Medicines Agency [EMA] reveal the company did not follow industry-standard quality management practices during preclinical toxicology studies as key studies did not meet good laboratory practice (GLP)., Neither reproductive toxicity nor genotoxicity (DNA mutation) studies were performed, both of which are considered critical when developing a new drug or vaccine for human use. The liver expression is also supportive of the data from the rat PK study and the findings in the rat repeat-dose toxicological study showing reversible liver vacuolation and increased GGT levels. which is it, did they or did they now know that the spike protein was a toxin/pathogenic for a long time? Most of the studies referenced by EMA are not available on the internet, but can be requested as was done by the Citizens petition. As questions intensify surrounding the true origins of SARS-CoV-2, the devastating discovery that spike proteins reach the bloodstream leaves wide open the door for many other legitimate questions about the long-term safety of COVID-19 vaccinesfor example, with it accumulating in the ovaries, will we be rendering some young people infertile?Bridle concluded: We made a big mistake; we didnt realize it until now. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines As of August 23, 2021, the Pfizer-BioNTech inoculation is now approved under the brand name Comirnaty. The more we learn about the COVID-19 vaccines, the worse they look. If you would like to help raise awareness of the facts surrounding children and COVID19 vaccines, please share. Ultimately at this juncture, it is a personal decision considering the risk vs. benefit ratio. When blood clots completely block a blood vessel, you end up with a stroke or a heart attack. Consistent data shows the virus is less severe than influenza in children, strengthening the argument of do kids need the vaccine? Voicing his concern, Bridle asserts: Thats not how this is supposed to work; our kids should not be the guinea pigs. In Japan, 10 fatal cases (five men and women) have been reported to date. The study has been supported financially by the Japan Agency for Medical Research and Development and Kitasato Institute. Okay I just noticed the link please ignore. Until recently, the opinion has been that these vaccines function like traditional vaccines and remain near the injection site. Canadian vaccine expert Dr. Byram Bridle recently spoke of the terrifying reasons serious side effects, including heart inflammation and vaccine-induced immune thrombotic thrombocytopenia (VITT), may occur in those who have received the COVID-19 vaccine. Perhaps the attached study will be helpful to her. Spike protein does not attack anything, it only aims to activate the immune response, it is not the same as coronavirus spike protein and after vaccination, it is created in a dose 100 thousand times lower than in viral infection. SARS-CoV-2 MRNA Vaccine (BNT162, PF-0 7302048)2.6.4 . It is necessary to understand their biodistribution. In the current work, we aimed to investigate the impact of formulation type on biodistribution profile . This review aimed at surveying international and Japanese trends concerning the BD study for CTPs and the following subjects were investigated, which were considered particularly important: 1) comparison of guidelines to understand the regulatory status of BD studies in a global setting; 2) case studies of the BD study using databases to understand its current status in cell therapy; 3) case studies on quantitative polymerase chain reaction (qPCR) used primarily in non-clinical BD studies for CTPs; and 4) survey of imaging methods used for non-clinical and clinical BD studies. Breastfeeding women also need to know that both the vaccine and the spike protein are being expelled in breast milk, and this could be lethal for their babies. The biodistribution was also studied in rats using radiolabeled LNP and luciferase modRNA (study 185350).. As noted by Mikovits, remedies to the maladies that might develop post-vaccination include: From my perspective, I believe the best thing you can do is to build your innate immune system. This means it was an experiment done with an animal model to predict where the vaccine formulation might go when injected into people. Some people, this gets into circulation, and when that happens, in some people, they can cause damage, especially to the cardiovascular system., https://uncoverdc.com/2021/05/31/vaccine-expert-warns-we-made-a-big-mistake/, In paragraph 3 you quote him as saying inter alia, regarding the spike protein that We thought the spike protein was a great target antigen; we never knew it was a toxin. However, para 8 he states We have known for a long time that the spike protein is a pathogenic protein. According to Kendrick, all of them have two things in common:12. The presentation summarized EMA requirements for BD study design, which include a dosing protocol that mimics the proposed clinical protocol with appropriate safety margins (usually highest dose), assessing all relevant organs, and extension of the analysis interval until the GT product is not detected or until a plateau phase is reached. Content Deleted, Powerful Billionaires Threaten Mercola, The Strange, New Pattern Showing Up After COVID Vaccine, New World Order Yields to the Great Reset, Worse Than The Disease: Reviewing Some Possible Unintended Consequences of mRNA Vaccines Against COVID-19, Princess of Thailand Potential Heiress to the Throne, Grassley: How My Investigation Into Biden Family Financial Dealings Was Sabo taged, Train Derailment Ground Zero Eye Report, New Palestine Train Derailment and Hazardous Materials, Mike Adams Editorial on Destruction of the Nordstream Pipeline, How America Took Out the Nordstream Pipeline, Reporter Seymour Hersh on How America Took Out the Nord Stream Pipeline: Exclusive TV Interview. Methods: This is a retrospective single-center study in 23 patients with COVID-19-induced ARDS. The attack causes damage to the lining, which results in inflammation. Theres also evidence suggesting the SARS-CoV-2 spike protein may be a prion, which is yet another piece of really bad news, particularly as it pertains to vaccine-induced spike protein. Using mRNA programmed to produce luciferase protein, as well as mRNA tagged with a radioactive label, Pfizer showed that the majority of the mRNA initially remain near the injection site, but within hours become widely distributed within the body.9. It can cause damage in our body if it gets into circulation The spike protein on its own is almost entirely responsible for the damage to the cardiovascular system, if it gets into circulation.. "Biodistribution" study of mRNA vaccines. Radioactivity was detected in most tissues from the first time point (0.25 h) and results support that injections site and the liver are the major sites of distribution. The petition and its supporting documents can be downloaded from the FDA website here: https://www.regulations.gov/docket/FDA-2021-P-0521/document, However, information regarding biodistribution of the Pfizer vaccine in animal studies was referenced by the European Medicine Agencys (EMA) review of Pfizers mRNA vaccine data sent to them by Pfizer. Elaborating on the implications of these findings, he remarked: We have known for a long time that the spike protein is a pathogenic protein. Other research suggests the SARS-CoV-2 spike protein can have a serious impact on your mitochondrial function, which is imperative for good health, innate immunity and disease prevention of all kinds.

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